PHD STUDENT

Project: “Cellular architecture of Archaea in the context of eukaryogenesis”

Laboratory of Structural Cell Biology,

Head: Dr. Piotr Szwedziak

 

POSITION IN PROJECT

PhD Student

SCIENTIFIC DISCIPLINE

Structural biology, molecular biology, biochemistry,

PROJECT NAME

"ReMedy"

PROJECT LEADER

Piotr Szwedziak /Laboratory of Structural Cell Biology,

SUBPROJECT NAME

“Cellular architecture of Archaea in the context of eukaryogenesis”

PROJECT DESCRIPTION

The main objective of this project is to structurally and functionally characterize primordial membrane remodelling complexes from a newly discovered archaeal branch and compare them to their ekuryotic counterparts. This project, which makes heaby use of biochemistry, is a great opportunity to learn cryoEM. For more information please contact Dr. Piotr Szwedziak p.szwedziak@imol.institute

Click to visit project's webpage for more information on project

NUMBER OF JOB OFFERS

1

REMUNERATION (PLN/MONTH):

3 500,00 – 4 000,00 PLN net; depends on experience

JOB TYPE

Full-time position, stipend

LOCATION

Warsaw, Poland

POSITION STARTS ON

1st June 2021 or later upon mutual agreement

APPLICATION DEADLINE

 19th May 2021

YOUR FUTURE KEY RESPONSIBILITIES:

  • Performing experiments using biochemical, structural and molecular biology techniques (independently and in collaboration with other team members),

  • Participation in experimental design and data analysis,

  • Participation in the data preparation and writing of manuscripts,

  • Active participation in lab meetings, scientific seminars and conferences.

IF YOU ARE:

  • MSc degree (or equivalent) in molecular biology, biophysics, biochemistry or related fields of life sciences (or perspective of obtaining one),

  • Solid knowledge and familiarity with laboratory techniques in at least one of the following disciplines: molecular biology, biochemistry, cell biology, genetics, transcriptomics,

  • Very good command of English,

  • Motivation and passion for experimental work.

... PLEASE APPLY.

And let us present the details to you.

REQUIRED DOCUMENTS

  • Motivation letter,

  • CV with the list of publications,

  • Contact details of the scientific supervisor and other referee/s if available (preferably including direct supervisor of applicant’s MSc thesis),

  • Please apply using the form below,

  • Please send all the documents as a single .pdf file, in English,

  • We will contact selected candidates only.

FNP PROGRAMME

  • Project is carried out within the International Research Agendas Programme of the Foundation for Polish Science

 

PhD position in electron cryomicroscopy available at the Laboratory of Structural Cell Biology

 

PhD position will be available in my lab, located at the Centre of New Technologies at the University of Warsaw, Poland. The successful candidate will investigate the organisation and architecture of archaeal cells at the molecular level. We utilise a multiscale approach, combining imaging across scales (X-ray, single particle cryoEM and fluorescence light microscopy bridged by electron cryotomography) with biochemistry.

 

The Centre of New Technologies is equipped with state-of-the-art instrumentation including: a dedicated Akta Pure system for large scale protein purification, UPLC- coupled Orbitrap for native mass spectrometry, computing cluster consisting of 646 CPUs and 366 GPUs, a Vitrobot plunge freezer, a 200 kV Glacios cryo-TEM fitted with a phase plate and a Falcon 3EC direct electron detector. Additionaly, we will have access to a Titan Krios G3i cryo-TEM equipped with a phase plate, BioQuantum energy filter and both K3 and Falcon3EC direct electron detectors located at the National Centre for Electron Cryomicroscopy in Kraków, Poland.

 

There are two FIB-SEM instruments (FEI Helios, Zeiss CrossBeam) at the campus that will be upgraded with a Leica cryostage to enable sample thinning prior to cryotomography imaging by micromachining of biological specimens in cryo conditions.

Piotr Szwedziak, PhD

 
 

SEND APPLICATION

PhD Student

Project: “Cellular architecture of Archaea in the context of eukaryogenesis”

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